Reducing the risk of (cross-)contamination, improving the Manicure tools chain of custody, providing fast analysis times and options of direct analysis at crime scenes: these requirements within forensic DNA analysis can be met upon using microfluidic devices.To become generally applied in forensics, the most important requirements for microfluidic
The risks posed to human health by individual animal prion diseases cannot be determined a priori and are difficult to address empirically.The fundamental event in prion disease pathogenesis is thought to be the seeded conversion of normal prion protein to its pathologic isoform.We used a rapid molecular conversion assay (protein Ski de fond - Enfa
The innate immune response to viral pathogens is critical in order to mobilize protective immunity.Cells of the innate immune system detect viral infection largely through germline-encoded pattern recognition receptors (PRRs) present either on the cell surface or within distinct intracellular compartments.These include the Toll-like receptors (TLRs
People sometimes solve problems with a unique process called insight, accompanied by an "Aha!" experience.It has long been unclear whether different cognitive and neural processes lead to insight versus noninsight solutions, or if solutions differ only in subsequent subjective feeling.Recent behavioral studies Overall indicate distinct patterns of
Eukaryotic protein kinases are well conserved through evolution.The genome of Schistosoma mansoni, which causes intestinal schistosomiasis, encodes over 250 putative protein kinases with all of the main eukaryotic groups represented.However, unraveling functional roles for Herbal Cream these kinases is a considerable endeavour, particularly as prot